What will result from the binding of a transcription factor to an enhancer region?

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Video Transcript

this question is asking about with the relationship between transcription factors and enhancers. So let's first establish what are transcription factors and enhancers. Transcription factors are proteins, and transcription factors are proteins that bind to regions of DNA. So, for example, these guys right here which recognize the Tato box these are transcription factors and proteins that also recognize enhancer regions are also transcription factors. So transcription factors are any sort of protein that can bind to D N A. That effects the transcription off a specific gene. Okay, No, what are enhancers enhancers? Refer to the inn A regions and enhancers are the regions which are far away from the d n A. That is being transcribed. So, for example, this enhanced the reason right here and this enhancer reason right here, which are coated in purple. They are very far away from the gene that is being transcribed. But because the DNA can loop around, these enhancer regions can bind transcription factors that can influence the ah rate at which that gene is being transcribed. And as the name suggests, enhancers increase the rate of transcription they enhanced right, so enhancers the results in an increase of transcription and enhancer regions are located far away from the DNA, but because the DEA, they are looking at far away from the gene that they regulate. But because the n A can loop around and bring regions that are thousands off nucleotides away from charter, they can bring them close together Through these looping action. That means that you can have regions of D N A that are far away from the gene that can affect how that gene is being transcribed, and enhancers are regions of the n A that increase the transcription off that gene. So now let's look at our answer choices Choice, eh? Is that enhancers result in a decrease transcription off on a Jason gene. Ah, that is wrong. For two reasons, Number one is that enhancers result in an increase of transcription. And number two is that they result in the increase of the transcription off a gene that is far away, not an adjacent gene choice. Be increased transcription of a decent gene. That is exactly what enhancer do. What enhancers Deuce Choice B is correct choice. See alteration off the translation often adjacent g mean Ah, that is not correct because number one. It is not Ah, the modulation, often adjacent Gene. And the second part is that it's not just alteration in general, it is the specific alteration off increasing the transcription. Okay, It's not like because alteration talks about you can either decrease or increase those air. Both alterations, no enhancers talk specifically about regions of d n A. Which increase Jean transcription. Okay, so choice he is not correct. Choice d is initiation off the recruitment off orange people Imerese That is the roll off general transcription factors which are down here. General transcription factors bind to the tot a box and that What is that? That's what recruits the Oran a prelim. A race to start transcribing the gene. Okay, the enhancers. That's not what they do. The enhancers. They recruit other proteins that enhance the transcription off that gene. So the only correct choice here is choice B. Ah that the ah binding off trance picked the binding off transcription factors to enhance the region's results in increased risk. Rip shin off a distant gene. Those are both key number one. You have increased transcription and a number two you have increased transcription at a distant gene

What happens when transcription factors bind to enhancers?

Other transcription factors bind to regulatory sequences, such as enhancer sequences, and can either stimulate or repress transcription of the related gene. These regulatory sequences can be thousands of base pairs upstream or downstream from the gene being transcribed.

What will result from the binding of a transcription factor to an enhancer region quizlet?

The binding of a transcription factor to an enhancer region will result in increased transcription of a distant gene because an enhancer increases the probability of a particular gene transcription.

What transcription factor binds to the enhancer region?

As detailed below, enhancers consist of dense clusters of transcription factor binding sites (TFBS) and are bound by cell type-specific TFs, coregulators, chromatin modifiers, architectural proteins like Cohesin, Condensin and CTCF, other enzymes, and RNAPII.

Can transcription factor bind to enhancer?

Binding of lineage-specific transcription factors to enhancers and promoters plays a vital role in the establishment/maintenance of long-range promoter–enhancer interactions.